Searchable abstracts of presentations at key conferences in endocrinology

ea0035p1107 | Thyroid Cancer | ECE2014

Effects of zoledronic acid monohydrate on cytotoxicity and apoptosis in BCPAP human papillary thyroid carcinoma cell line

Simsir Ilgin Yildirim , Kocabas Gokcen Unal , Yurekli Banu Pinar Sarer , Avci Cigir Biray , Saygili Lutfiye Fusun

Thyroid cancer in Turkey is the most common endocrine neoplasm with an incidence of 3.7%. Papillary thyroid carcinoma is the most common thyroid malignancy in a similar manner. Papillary thyroid carcinoma creates 50–90% of differentiated thyroid carcinomas. There is available in subgroups with poor prognosis. Case-specific mortality of 2% at 5, 10, and 20 years, only 4 and 5%.Mutations and re-arrangements in genes encoding proteins of the MAPK pathw...

ea0056p847 | Pituitary - Clinical | ECE2018

The Secret of the Ophtalmopathy

Simsir Ilgin Yildirim , Soyaltin Utku Erdem , Yurekli Banu Sarer , Yilmaz Mumtaz , Saygili Fusun

Although the first line therapy for prolactinoma is medical. Visual field defect due to pituitary mass would lead to surgery. Herein, we share the post-operative follow-up of a macroprolactinoma case.Case: A 57-year-old male patient was operated on for a giant pituitary adenoma, which was compressing the optic chiasm. The postop prolactin (PL) value was found to be higher than 200 ng/ml and cabergoline treatment was initiated. Two months after the operat...

ea0056ep107 | Pituitary and Neuroendocrinology | ECE2018

Could it be recurrent immunoglobulin G4-associated inflammatory mass at the hypothalamic region?

Erdem Soyaltin Utku , Simsir Ilgin Yildirim , Yurekli Banu Sarer , Saygili Fusun

Case: Thirty seven years old patient whose complaint was head ache was seen in the out patient clinic for the follow up of her hormone replacement therapy. First time she was admitted to hospital with the complaint of confusion was in 2013. Her cranial MRI revelaed enlargement of optic chiasma with the possible diagnossis of optic chiasmatic glioma. Biopsy was taken out from this mass twice in July and November of 2013. In histological examinations, there were B and T lymphocy...

ea0090ep259 | Diabetes, Obesity, Metabolism and Nutrition | ECE2023

COVID-19 infection in lipodystrophy syndromes

Semiz Gokcen Gungor , Demir Tevfik , Simsir Ilgin Yildirim , Selimoğlu İsmail , Yılmaz Muge , Unal Mehmet Cağrı , Ellidıkuz Hulya , Onay Huseyin , Gen Ramazan , Evren Bahri

Purpose: The coronavirus disease 2019 (COVID-19) has a high morbidity and mortality in patients with chronic disorders. This study was aimed at assessing the frequency and outcomes of COVID-19 in patients with lipodystrophy syndrome and investigating the effect of restricted access to the hospital during pandemic on metabolic parameters.Methods: A survey comprising descriptive questions about the situation of the patients during the COVID-19 pandemic was...

ea0037ep345 | Diabetes (pathiophysiology & epitemiology) | ECE2015

Acquired partial lipodystrophy is associated with increased risk for metabolic complications

Akinci Baris , Koseoglu Fatos , Onay Huseyin , Yavuz Sevgi , Altay Canan , Simsir Ilgin Yildirim , Ozisik Secil , Demir Leyla , Korkut Meltem , Yilmaz Nusret , Ozen Samim , Akinci Gulcin , Atik Tahir , Calan Mehmet , Secil Mustafa , Comlekci Abdurrahman , Demir Tevfik

Objective: Acquired partial lipodystrophy (APL) is a rare disorder characterized by progressive selective fat loss. In previous studies, metabolic complications were reported to be relatively rare in APL, while they were quite common in other types of lipodystrophy syndromes. However, so far, there has been no systematic study on metabolic complications in APL.Methods: We have systematically evaluated 21 APL patients in the Turkish Lipodystrophy Study Gr...